The prognosis for malignant mesothelioma is still disappointing, although due to new types of chemotherapy and multifunctional therapies, some improvements have been shown. In the early stages, the diagnosis of malignant mesothelioma is better, but completely The cases of recovery are very rare. There are many factors that affect the diagnosis of malignancy, including the continuous mesothelial surface of the pleural cavity, which supports local metastasis through unforeseen cells, invasion of intertidal tissue and other organs located within the pleural cavity, and contact with asbestos And there is an extremely long latency period between the development of the disease. Histological subtype and patient's age and health status also help in diagnosing diagnosis.
For patients with delicate disease and for those who can afford a full surgery, often radiation is used as a joint treatment after surgery. The entire half-part of the chest is treated by the radiation method, which is often given with chemotherapy. This method of using radiation with chemotherapy after surgery was initiated by thoracic oncology team of Brigham and Women's Hospital in Boston.
After the use of radiation and chemotherapy after a complete surgery, the survival of a selected group of patients has increased and some of these patients also survived for more than 5 years. As part of a hygienic method against mesothelioma, radiotherapy is also used at the entry points of the chest exhaust tube, so that the tumor's development can be stopped on this path in the chest wall.
Chemotherapy is the only surgery for mesothelioma, which has proven to increase survival in uncontrolled and controlled trials. In a historical study published in 2003, by Wogelzang and his colleagues, the singular cisplatin chemotherapy compared with the combination of Sisplatin and pemetrexed (brand name Alimta) chemotherapy was done in patients who had not been given Chemotherapy for previously malignant pleural mesothelioma. And who were not more aggressive "remedial" surgery candidates